Heart Rate Variability and neurovegetative Regulation

A well functioning neurovegetative regulation is the key to health and well-being. The state of the neurovegetative regulation is recognizable by the change in heart rate, the so-called heart rate variability (HRV).hrv1

ECG curve of a healthy person with different intervalls between the single heartbeats.

Our “internal brake”, the parasympathetic nervous system with its main nerve (vagus nerve) can optimally regulate the processes in the body. An effective parasympathetic leads to a tight synchronization of breathing and heart frequency, which is called respiratory sinus arrhythmia (RSA) ,


Optimal parasympathetic regulation of the heart rate of a healthy, sporty person. The increase of the heart rate when inhaling and its fall during exhalation as an expression of a healthy and powerful parasympathetic is clearly visible.

Just as good respiratory sinus arrhythmia suggests a healthy parasympathetic, a lack of synchronization between respiration and heartbeat is a clear indication of insufficient parasympathetic activity.


Heart rate curve of a person with high chronic stress. Despite deep breathing, respiratory sinus arrhythmia (RSA) is absent, the parasympathetic is weak and has no influence on the heart.

Our parasympathetic is sensitive to damaging influences. Chronic stress, lack of sports, an unfavorable lifestyle and various diseases lead to “parasympathetic dysfunction”. If this malfunction of the parasympathetic maintains for a longer time, health will suffer. There are now well-founded indications that a weakness of the parasympathetic is in causal connection with the occurrence of cardiovascular diseases, cancer and Alzheimer’s.

„You may need the vagus nerve to understand pathophysiology and to treat diseases“

Marijke DE COUCK, Boris MRAVEC and Yori GIDRON, Clinical Science (2012) 122, 323–328


Protective effect of a functioning parasympathetic, visible by a high HRV, on the harmful effects of risk factors

BioSign is a pioneer in the field of autonomous functional diagnostics and has first developed the RSA measurement, originally a complex HRV test in highly specialized autonomous functional laboratories, to an easy-to-use “brake test” for all who are interested in the parasympathetic functional testing.

Further HRV measurements from BioSign such as the Short-Term HRV, Supine/ Standing, 24-hour HRV and point-of-care HRV (patient self-measurement at home) allow an even closer look at vegetative regulation. BioSign offers an innovative training facility for the improvement of neurovegetative regulation by means of HRV Biofeedback.


Example 24-hour analysis for the detection of stress situations in everyday life and for the assessment of regeneration during sleep.